Read e-book online Antibiotic Discovery and Development PDF

By Thomas J. Dougherty,Michael J. Pucci

ISBN-10: 1461413990

ISBN-13: 9781461413998

ISBN-10: 1489978224

ISBN-13: 9781489978226

This quantity covers all facets of the antibiotic discovery and improvement strategy via section II/III. The individuals, a bunch of hugely skilled contributors in either teachers and undefined, comprise chapters at the want for brand new antibiotic compounds, ideas for screening for brand new antibiotics, resources of novel artificial and typical antibiotics, discovery stages of lead improvement and optimization, and candidate compound nominations into improvement. past discovery , the guide will disguise all the reports to organize for IND submission: section I (safety and dose ranging), development to section II (efficacy), and part III (capturing wanted preliminary indications). This publication walks the reader via all features of the method, which hasn't ever been performed prior to in one reference. With the increase of antibiotic resistance and the expanding view trouble might be looming in infectious illnesses, there are powerful symptoms of renewed emphasis in antibiotic examine. the aim of the guide is to supply an in depth evaluate of all points of the matter posed via antibiotic discovery and development.

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Antibiotic Discovery and Development by Thomas J. Dougherty,Michael J. Pucci

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