By Mark C. Williams,III, L. James Maher
Depite the speedy growth of the sphere of biophysics, there are only a few books that comprehensively deal with particular issues during this sector. lately, the sector of unmarried molecule biophysics has constructed in a short time, and some books in particular treating unmarried molecule tools are starting to seem. in spite of the fact that, the promise of unmarried molecule biophysics is to give a contribution to the certainty of particular fields of biology utilizing new tools. This booklet might concentrate on the explicit subject of the biophysics of DNA-protein interactions, and would come with using new techniques, together with either bulk equipment in addition to unmarried molecule equipment. this may make the publication beautiful to somebody operating within the normal region of DNA-protein interactions, that is after all a much broader industry than simply unmarried molecule biophysicists or perhaps biophysicists.
The topic of the ebook stands out as the biophysics of DNA-protein interactions, and may contain new equipment and effects that describe the actual mechanism during which proteins have interaction with DNA. for instance, there was a lot fresh paintings at the mechanism during which proteins look for particular binding websites on DNA. a couple of chapters might be dedicated to experiments and idea that make clear this crucial challenge. we'll additionally disguise proteins that adjust DNA homes to facilitate interactions vital for transcription or replication. one other part of the booklet will conceal the biophysical mechanism in which motor proteins have interaction with DNA. eventually, we are going to conceal better protein-DNA complexes, comparable to replication forks, recombination complexes, DNA fix interactions, and their chromatin context.
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Extra info for Biophysics of DNA-Protein Interactions: From Single Molecules to Biological Systems (Biological and Medical Physics, Biomedical Engineering)
Biophysics of DNA-Protein Interactions: From Single Molecules to Biological Systems (Biological and Medical Physics, Biomedical Engineering) by Mark C. Williams,III, L. James Maher