By Ksenia Guseva
With the purpose of offering a deeper perception into attainable mechanisms of organic self-organization, this thesis offers new ways to explain the method of self-assembly and the influence of spatial association at the functionality of membrane proteins, from a statistical physics perspective. It specializes in 3 vital situations: the meeting of membrane proteins, the collective reaction of mechanosensitive channels and the functionality of the dual arginine translocation (Tat) procedure. utilizing tools from equilibrium and non-equilibrium statistical mechanics, normal conclusions have been drawn that exhibit the significance of the protein-protein interactions. specifically, within the first half a basic aggregation dynamics version is formulated, and used to teach that fragmentation crucially impacts the potency of the self-assembly strategy of proteins. within the moment half, via mapping the membrane-mediated forces right into a simplified many-body procedure, the dynamic and equilibrium behaviour of interacting mechanosensitive channels is derived, displaying that protein agglomeration strongly affects its wanted functionality. the ultimate half develops a version that includes either the agglomeration and delivery functionality of the Tat procedure, thereby delivering a entire description of this self-organizing process.